Zoekresultaten - 32 results
Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing
Vanneste Source: Frontiers in Microbiology, Volume 12 (2021) Keywords: co-infection Illumina NGS quasispecies SARS-CoV-2 variant of concern wastewater surveillance Abstract: The ongoing COVID-19 pandemic, ...
Precision cancer medicine: What has translated into clinical use in Belgium?
Cancer Biol (2021) Keywords: cancer EVALUATION implementation Precision Medicine Abstract: RATIONALE: In 2016, Belgium launched the Next Generation Sequencing (NGS) Roadbook, consisting in 10 Actions, ...
Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination.
localized on plasmids can be easily transferred between bacterial isolates by horizontal gene transfer, thereby contributing to the spread of AMR. Next-generation sequencing (NGS) technologies are ideal for ...
Perceived utility and feasibility of pathogen genomics for public health practice: a survey among public health professionals working in the field of infectious diseases, Belgium, 2019
gather the opinions of public health experts and allied professionals working in the field of infectious diseases in Belgium concerning the implementation of next-generation sequencing (NGS) in public ...
Combining short and long read sequencing to characterize antimicrobial resistance genes on plasmids applied to an unauthorized genetically modified Bacillus
Nancy Roosens; Sigrid C.J. De Keersmaecker Source: Scientific Reports, Volume 10, Issue 1 (2020) Keywords: AMR GMM long and short read sequencing NGS Plasmids Abstract: Antimicrobial resistance (AMR) is ...
NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program
assessment; cancer Abstract: Next-generation sequencing (NGS) is being integrated into routine clinical practice in the field of (hemato-) oncology to search for variants with diagnostic, prognostic, or ...
Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza
antiviral resistance INFLUENZA Next-generation sequencing Surveillance Abstract: Next-generation sequencing (NGS) can enable a more effective response to a wide range of communicable disease threats, such as ...
Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel.
(NGS) is currently the default assay for the detection of somatic variants in solid as well as haematological tumours. Independent of the method, the final outcome is a list of variants that differ from ...
Diagnostic testing in myeloid malignancies by next-generation sequencing: recommendations from the commission personalised medicine
Commission of Personalised Medicine was founded to give professional and evidence-based advice on the molecular analysis in haemato-oncology. This paper describes its recommendations for NGS analysis in ...
Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.
observation spurred the development of an in silico workflow which extracts the Shigella serotype from Next-Generation Sequencing (NGS) data, taking into account gene functionality. Both tools will be ...