Zoekresultaten - 39 results

The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review

parasites harboring mutations related to mefloquine-resistance, but we could suspect those with decreased susceptibility to quinine, amodiaquine, and lumefantrine based on corresponding molecular surrogates. ...

Animal sources of antimicrobial-resistant bacterial infections in humans: a systematic review

defined as livestock, aquaculture, pets, and animal-based food, on human AMR. We searched four scientific databases and identified 31 relevant publications, including 12 risk assessments, 16 source ...

Report on the feasibility of using Hi-C sequencing for metagenomics to define the context of AMR genes

Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: Sigrid C.J. De Keersmaecker; Josephine Grützke; Carlus Deneke; Jennie Fischer; Lee Julia Bartsch; Bram Bloemen; Kevin Vanneste; Jolien D'aes; Nancy Roosens; Man ...

Report on initial findings of on-site diagnostic tests and IT solutions for human clinical, veterinary and environmental samples for early warning of emerging resistant pathogens

https://doi.org/10.5281/zenodo.7433281 URL: https://doi.org/10.5281/zenodo.7433281 Keywords: Long read metagenomics Metagenome On-site metagenomics Health Topics:  Antimicrobial resistance (AMR) Food consumption and food safety Animal ...

MRSA surveillance programmes worldwide: moving towards a harmonised international approach

Keywords: Antimicrobial resistance epidemiology Staphylococcus aureus Abstract: Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national ...

Fluoroquinolone resistance in Escherichia coli isolates after exposure to non-fluoroquinolone antibiotics: a retrospective case–control study

tertiary care patients in Belgium with information on prior antibiotic use at the patient level up to 1 year previously. Results In urine samples from 6125 patients, 7204 E. coli isolates were retrieved ...

Genomic epidemiology of emerging ESBL-producing Kentucky in Europe.

urinary-tract infections. Bayesian time-scaled phylogeny on whole genome sequences of isolates from these cases and supplementary isolates from public sequence databases was used to infer the origin and spread of ...

Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.

J (2020) Abstract: Conventional molecular tests for detecting complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole genome sequencing (WGS) typically requires culture. ...

Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination.

localized on plasmids can be easily transferred between bacterial isolates by horizontal gene transfer, thereby contributing to the spread of AMR. Next-generation sequencing (NGS) technologies are ideal for ...

Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance.

national policies as a first-line treatment for uncomplicated malaria in several endemic countries, such as the Democratic Republic of Congo (DRC). The K76T mutation on the pfcrt gene has been identified as ...

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