Zoekresultaten - 9 results

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.

inhibition assay allows the phenotypical identification of resistant strains; however, this test often has limited sensitivity with high variability depending on the virus strain, drugs and assays. Once ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

polymerase Abstract: The optimized exploitation of cell resources is one cornerstone of a successful infection. Differential mapping of host-pathogen protein-protein interactions (PPI s) on the basis of ...

Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015-2016.

Publication Type: Peer reviewed scientific article Authors: Joana Revez; Laura Espinosa; Barbara Albiger; Katrin Claire Leitmeyer; Marc Jean Struelens; Steven Van Gucht Source: Front Public Health, Volume 5 (2017) Keywords: infectious disease sequencing S ...

Overlapping signals for translational regulation and packaging of influenza A virus segment 2.

mutated AUG s 1-4 and monitored polypeptide synthesis from plasmids and recombinant viruses. This identified sORF2 as a key regulatory element with opposing effects on PB1- F2 and PB1- N40 expression. We ...

Temperature sensitivity on growth and/or replication of H1N1, H1N2 and H3N2 influenza A viruses isolated from pigs and birds in mammalian cells.

viruses belonging to different lineages isolated from birds or pigs prior to 2005 was tested on MDCK or NPT r cell lines in the presence or absence of exogenous trypsin. Virus multiplication was compared at ...

Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes.

Publication Type: Peer reviewed scientific article Authors: Bernadette Crescenzo-Chaigne; Cyril Barbezange; Sylvie van der Werf Source: Virol J, Volume 5 (2008) Keywords: Base Sequence DNA Replication Influenzavirus C Molecular Sequence Data Nucleoprotein ...

The impact of regular school closure on seasonal influenza epidemics: a data-driven spatial transmission model for Belgium.

parameterized with country-specific data on social mixing and travel, and calibrated to the 2008/2009 influenza season. It includes behavioral changes occurring during weekend vs. weekday, and holiday vs. ...

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