Zoekresultaten - 10 results
The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.
p-value, and if the lower bound of the 95% confidence interval on the positive predictive value for phenotypic resistance was >25%. A series of expert rules were applied for final confidence grading of ...
Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.
extraction procedures. Few multicentre studies on the reproducibility of MALDI- TOF have been performed so far, none on mycobacteria. The aim of this study was to evaluate the reproducibility of MALDI- TOF for ...
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
insufficient to support the use of WGS as an alternative to conventional phenotype-based DST, due to mutation catalogue limitations. Here we present a new tool,, which provides the same functionality based on ...
Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.
Werf; F Drobniewski; V Nikolayevskyy Source: Int J Tuberc Lung Dis, Volume 22, Issue 4 (2018) Keywords: hands-on time laboratory diagnosis Workload Abstract: SETTING: Implementation of novel diagnostic ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
and Sudan. METHODS: On April 29 and May 30, 2016, the Swiss and German National Mycobacterial Reference Laboratories independently triggered an outbreak investigation after four patients were diagnosed with ...
MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
method is more challenging due to the special need for inactivation and protein extraction. Although several studies have been published, there is no clear consensus on the processing of Mycobacteria for ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...
Multicentric study on the improved identification of Non-Tuberculous Mycobacteria with MALDI-TOF MS using three different preprocessing protocols
Publication Type: Scientific poster, presentation or proceeding Authors: EU Mycobacteria-MALDI study group; An Van den Bossche; Pieter-Jan Ceyssens Source: ECCMID 2017, Issue ESCMID, Vienna, Austria (2017) Health Topics: Tuberculosis Tuberculose Tubercul ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Vanessa Mathys; Pieter-Jan Ceyssens Source: 2nd St. Petersburg Symposium on Tuberculosis and Mycobacteria: Molecular Approach, Issue Institut Pasteur Sint Petersburg, Sint Petersburg (2018) Abstract: ...