Zoekresultaten - 23 results
Pyrogen testing of phage therapeutic products
cell wall, flagellin, etc. are not detected by those tests. As phages are being produced in a growing variety of bacterial host strains, including gram-positive bacteria, an expansion of the QC workflow ...
Evaluation of a point-of-care test for the diagnosis of Taenia solium neurocysticercosis in rural southern Tanzania: a diagnostic accuracy study.
tools. This study evaluated the diagnostic accuracy of a T solium cysticercosis antibody-detecting lateral-flow point-of-care assay (TS POC test) for the neuroimaging-based diagnosis of neurocysticercosis. ...
The GEONs API-fingerprint program: Tackling falsifications of APIs
casualties happened when altered API s escaped detection in routine analytical testing. Any form of tampering the content or information about the content might affect the quality of the API, the finished ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
that could be implemented for routine potency assessment of vaccines. Our work focused on the development of a Luminex-based multiplex assay (four to six-plex assay depending on the number of pertussis ...
Chemical and toxciological characterization of e-liquid cigarettes
e-liquid refills. First, a comprehensive literature search was performed to obtain an overview about the chemical composition of the e-liquids and the analytical methods used for their detection. Although the ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
a subsequent quantification method using ultra-high performance liquid chromatography with diode array detection (UHPLC- DAD) was also successfully validated. Next, real-life illegal antimicrobial samples, ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
(MS) and quantification via UV. Validation was performed via accuracy profiles based on the ISO 17025 guideline. The obtained validated HILIC-method allows for the detection and quantification of the ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
compressed into tablets or capsules. The classical identification approaches based on micro- and macroscopy are therefore not possible anymore. In this paper infrared spectroscopy, combined with attenuated ...
Detection and risk evaluation of counterfeit medicines based on physico-chemical properties: the fingerprint and chemometrics approach
since even very low concentrations of API could be detected while these particular samples are classified as placebo based on other types of fingerprints. Illegal slimming aids do not only pose a threat ...
The Monte Carlo validation framework for the discriminant partial least squares model extended with variable selection methods applied to authenticity studies of Viagra® based on chromatographic impurity profiles.
based on the Monte Carlo approach that is used in the context of authenticity studies based on chromatographic impurity profiles. The performance of the validation approach was applied to evaluate the ...