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Zoekresultaten - 48 results
Combined deficient response to polysaccharide-based and protein-based vaccines predicts a severe clinical phenotype
Publication Type: Peer reviewed scientific article Authors: Cockx, Maaike; Haerynck, Filomeen; Hoste, Levi; Schrijvers, Rik; Van der Werff ten Bosch, Jutte; Dillaerts, Doreen; Thomas, Debby; Schaballie, Heidi; Bucciol, Giorgia; Robberechts, Wiert; Patel, ...
ELM-the Eukaryotic Linear Motif resource-2024 update.
structural and functional components of modular eukaryotic proteins. They are also the most abundant, especially when considering post-translational modifications. As well as being found throughout the cell as ...
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
urgently needed to develop alternative therapies. One path explored in this article is the use of bacteriophages and, more specifically, phage-derived proteins. In this study, a phage-derived protein was ...
Microbial quality analysis of falsified medicines seized by controling agencies
are known to be encoding proteins that can cause gastrointestinal illness upon ingestion. These results indicate that at least 16 samples from the 32 substandard and falsified medicinal products ...
Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.
Pritisanac, Iva; Tenorio, Luiggi; Viennet, Thibault; Tompa, Peter; Vranken, Wim; Tosatto, Silvio C E; Davey, Norman E Source: Nat Methods, Volume 20, Issue 9 (2023) Keywords: Intrinsically Disordered Proteins ...
Applicability of the DPRA on mixture testing: challenges and opportunities.
Keywords: Animal Testing Alternatives Animals Peptides Abstract: The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the ...
Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples
RT-ddPCR method that targets the T19I amino acid mutation in the spike protein of the SARS-CoV-2 genomes, which is specific to the BA.2 variant (omicron). The T19I assay was evaluated both in silico and in ...
Identification of Mycobacterium abscessus Subspecies by MALDI-TOF Mass Spectrometry and Machine Learning.
challenging. In this study, a collection of 325 clinical isolates of M. abscessus was used for MALDI- TOF MS analysis and for the development of machine learning predictive models based on MALDI- TOF MS protein ...
Telacebec Interferes with Virulence Lipid Biosynthesis Protein Expression and Sensitizes to Other Antibiotics
Publication Type: Peer reviewed scientific article Authors: Zhou, Zhiyu; Wattiez, Ruddy; Constant, Patricia; Marrakchi, Hedia; Karine Soetaert; Vanessa Mathys; Fontaine, Véronique; Zeng, Sheng Source: Microorganisms, Volume 11, Issue 10 (2023) Health Topi ...
From b to y ions, a decade of experience with peptide and protein analysis
recombinant expression technologies, and peptide synthesis have led to an increased development of protein and peptide therapeutics. Due to improved and simplified manufacturing techniques, disregard for patent ...