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Zoekresultaten - 90 results
Public microbial resources centres: key hubs for FAIR microorganisms and genetic materials.
microbiology, microbial domain biological resource centres (mBRCs) have a long-standing experience in preserving and distributing authenticated microbial strains and genetic materials (e.g., recombinant plasmids, ...
Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.
responsible for millions of episodes of bacterial dysenteriae worldwide. Given its distinct epidemiology and public health relevance, only Shigellae are subject to mandatory reporting and follow-up by public ...
Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing
circulating, pre-pandemic H1N1 virus and, along with H3N2 viruses, are now responsible for the seasonal influenza type A epidemics. So far, the evolutionary potential of influenza viruses has been mainly ...
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
NF-κB signaling and a cysteine protease that cleaves substrates, leading to the expression of immunoregulatory genes. Here, we examined the impact of genetic or pharmacological MALT1 inhibition in mice on ...
Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection
lungs, spleen and liver and mycobacteria specific spleen cell IFN-γ, IL-10 and IL-17 production as well as serum antibody responses were analyzed. Isolates varied in virulence, with human and porcine ...
Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection.
liver and mycobacteria specific spleen cell IFN-γ, IL-10 and IL-17 production as well as serum antibody responses were analyzed. Isolates varied in virulence, with human and porcine isolates sharing MST22 ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
C-epsilon rats Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Transduction, Genetic Abstract: A critical role has been assigned to protein kinase C (PKC)ε in the control of intracellular calcium ...
Genetic elements associated with antimicrobial resistance among avian pathogenic Escherichia coli.
(APEC) are pathogenic strains of E. coli that are responsible for one of the most predominant bacterial disease affecting poultry worldwide called avian colibacillosis. This study describes the genetic ...
Cryptococcus neoformans population diversity and clinical outcomes of HIV-associated cryptococcal meningitis patients in Zimbabwe.
Adult Cryptococcus neoformans Female Genetic Variation Genotype HIV Infections Humans Male Meningitis, Cryptococcal middle aged Prospective Studies Young adult Zimbabwe Abstract: HIV and cryptococcal ...
Scalable chromatography-based purification of virus-like particle carrier for epitope based influenza A vaccine produced in Escherichia coli.
diagnostic tools, and gene therapy vectors. Size, oligomer assembly and repetitiveness of epitopes are optimal features to induce strong immune responses. Several VLP-based vaccines are currently licensed and ...