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Zoekresultaten - 17 results
Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.
used to study the factors behind this output in more detail. Further studies demonstrated that the more severe disease outcome associated with the MDCK-clone involves a strong induction of ...
Screening for nanoparticles in complex matrices within a regulatory framework: are we there yet?
particle inductively coupled plasma – mass spectrometry (spICP- MS) was studied as a screening tool to determine the number-based size distribution of Ag particles, their particle number and mass ...
MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.
DPI. A decreased induction of inflammatory gene expression and cell infiltration and activation was observed in MALT1-/- mice at 10DPI as compared to MALT1 +/+ infected mice. At 17 DPI, however, ...
Reduced virulence of a pseudorabies virus isolate from wild boar origin in domestic pigs correlates with hampered visceral spread and age-dependent reduced neuroinvasive capacity.
efficiently suppressed in the trigeminal ganglion in the presence of a moderate induction of cytokine-related mRNA. Viral replication in the peripheral and central nervous system of 15-week-old pigs was limited ...
Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines
identifying the receptor involved in the recognition of several PAMP s. Furthermore, we showed that the activation of this receptor by these mycolate esters triggers the induction of protective Th1 and Th17 ...
Age-Dependent Differences in Pseudorabies Virus Neuropathogenesis and Associated Cytokine Expression.
15-week-old pigs, viral replication was efficiently suppressed in the TG and CNS without induction of an extensive immune response. Furthermore, our results provide evidence that neurological disease could, at ...
Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.
Transduction Tuberculosis Vaccines Vaccines, Subunit Abstract: INTRODUCTION: Pathogen recognition receptors (PRR s) recognize pathogen-associated molecular patterns, triggering the induction of inflammatory ...
Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis.
premature rupture of the membranes, chorioamnionitis, mode of delivery, length of labour, induction of delivery, oxytocin use, haemorrhage, analgesia, cervical cerclage, and cervical stenosis. Neonatal ...
Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.
to which nanoparticles contribute to cellular toxicity is known to associate induction of oxidative stress. To investigate this problem further, the effect of titanium dioxide nanoparticles was ...
Scientific Opinion on the Risks for human health related to the presence of 3- and 2-monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food
for induction of renal tubular hyperplasia in rats and derived a tolerable daily intake (TDI) of 0.8 µg/kg bw per day. The mean exposure to 3- MCPD was above the TDI for 'Infants', ...