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Zoekresultaten - 5 results
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
The Vitotox and ToxTracker assays: a two-test combination for quick and reliable assessment of genotoxic hazards
Publication Type: Peer reviewed scientific article Authors: Ates, Gamze; Favyts, Dorien; Hendriks, Giel; Derr, Remco; Birgit Mertens; Luc Verschaeve; Rogiers, Vera; Tatyana Yordanova Doktorova ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Publication Type: Peer reviewed scientific article Authors: Herwig, R; Gmuender, H; Corvi, R; Bloch, K M; Brandenburg, A; Castell, J; Ceelen, L; Chesne, C; Doktorova, T Y; Jennen, D; Jennings, P; ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
Publication Type: Peer reviewed scientific article Authors: Ates, Gamze; Steinmetz, Fabian P; Doktorova, Tatyana Yordanova; Madden, Judith C; Rogiers, Vera Source: Regul Toxicol Pharmacol, Volume ...