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Zoekresultaten - 10 results

A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells

Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid ...

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

GENOMARK, a promising new approach methodology for genotoxicity testing in the cosmetic industry

International cosmetic congress, Antalya, Turkey (2022) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

European Society of Mycobacteriology, ESM, Issue ESM, Sibenik, Craotia (2017) Keywords: antibiotics Mycobacterium tuberculosis Transcriptomics Abstract: Background: With 1.5 million deaths in 2014, the most ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

ESCMID, Vienna, Austria (2017) Keywords: antibiotics Mycobacterium tuberculosis Transcriptomics Abstract: Background: With 1.5 million deaths in 2014, the most recent report of the WHO ranks tuberculosis ...

Modulation of early beta-defensin-2 production as a mechanism developed by type I Toxoplasma gondii to evade human intestinal immunity36564

strains. Transcriptome analysis revealed that among differentially expressed genes, beta-defensins distinguished the most IEC infected by fast- or slow-replicating T. gondii genotypes. Although beta-defensin ...

RNA sequencing-based transcriptional overview of xerotolerance in Cronobacter sakazakii SP291.

formula, often resulting in high mortality rates. Here, we used transcriptome sequencing (RNA-seq) to provide transcriptional insights into the survival of  C.  sakazakii  in desiccated conditions. Our  ...

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.

Source: Tuberculosis (Edinb), Volume 117 (2019) Keywords: Mycobacterium tuberculosis Nitroimidazoles Transcriptome Abstract: Tuberculosis (TB) is the most deadly infectious disease worldwide. To reduce TB ...

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