Zoekresultaten - 53 results

Novel GMO-Based Vaccines against Tuberculosis: State of the Art and Biosafety Considerations.

p.463-99 (2014) Abstract: Novel efficient vaccines are needed to control tuberculosis (TB), a major cause of morbidity and mortality worldwide. Several TB vaccine candidates are currently in clinical and ...

1,2,3,4,8,9,10,11-Octahydrobenzo[j]phenanthridine-7,12-diones as New Leads against Mycobacterium tuberculosis

Research resistance Service strain study Target toxicity Tuberculosis vaccine vaccines Abstract: Tuberculosis (TB) continues to be a worldwide health problem with over 1.4 million deaths each year. Despite ...

Increasing the Vaccine Potential of Live M. bovis BCG by Coadministration with Plasmid DNA Encoding a Tuberculosis Prototype Antigen.

IS M mice neonate neonates observed ON protocol Pulmonary response Responses result results specific Spleen Still study Tuberculosis Vaccination vaccine Vector Abstract: The attenuated live M. bovis ...

Use of Strep-tag II for rapid detection and purification of Mycobacterium tuberculosis recombinant antigens secreted by Streptomyces lividans

Tuberculosis Universities university use vaccine Abstract: Recent results with respect to the secretory production of bio-active Mycobacterium tuberculosis proteins in Streptomyces have stimulated the further ...

Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377

tuberculosis need production profile Pulmonary recombinant response Responses result results SAFETY Salmonella Spleen study Tuberculosis Type Vaccination vaccine Abstract: Pulmonary vaccination is a promising ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycolic Acids Organ Specificity Oxygen Species Specificity Spleen Th1 Cells Th17 Cells Trachea Treatment Outcome Tuberculosis Vaccination virulence ...

Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028

production protection Pulmonary Ratio Research Research Support residence response Responses SAFETY SB- IM specific Spleen study Target Targets time Tuberculosis Vaccination vaccine Abstract: The current ...

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis34032

Switzerland Test time Times Tuberculosis Tuberculosis,Pulmonary Universities university university hospital Vaccination vaccine vaccines varieties variety Abstract: Vaccination with Mycobacterium bovis BCG ...

An update on vaccines for tuberculosis- there is more to it than just waning of BCG efficacy with time.

Trials, Phase I as Topic Clinical Trials, Phase II as Topic Humans Tuberculosis Tuberculosis Vaccines Abstract: INTRODUCTION: Apart from better diagnostics and new anti-microbial drugs, an effective vaccine ...

DNA vaccines for the prophylaxis of TB

Publication Type: Scientific book or chapter Authors: Marta Romano; K Huygen; Nor,N.M.; Acosta,A.; Sarmiento,M.E. Source: The Art and Science of Tuberculosis Vaccine Development, Oxford Fajar Sdb ...

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