Zoekresultaten - 53 results
Evaluation of the immunogenicity of pBudCE4.1 plasmids encoding mycolyl-transferase Ag85A and phosphate transport receptor PstS-3 from Mycobacterium tuberculosis.
Acyltransferases Animals ATP-Binding Cassette Transporters Bacterial Proteins Bacterial Vaccines Base Sequence DNA Primers Female mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Plasmids ...
Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.
mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...
Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.
Enzyme-Linked Immunosorbent Assay Immunization, Secondary Interferon-gamma Interleukin-17 mice Mice, Inbred BALB C Mycobacterium tuberculosis Survival Analysis T-Lymphocyte Subsets Tuberculosis Vaccines, DNA ...
Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle16
Tuberculosis vaccine young Abstract: The characterization of protective antigens is essential for the development of an effective, subunit-based vaccine against paratuberculosis. Surface-exposed and secreted ...
Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.
Histocompatibility Antigen H-2D Interferon-gamma Interleukin-2 mice Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines Vaccines, DNA ...
Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis.
Immunization mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis Th1 Cells Tuberculosis Vaccines Tuberculosis, Pulmonary Vaccines, DNA Abstract: BALB /c (H-2(d)) and ...
Improved tuberculosis DNA vaccines by formulation in cationic lipids.
Phosphatidylethanolamines Spleen T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccination Vaccines, DNA Abstract: Mice were vaccinated with plasmid DNA (pDNA) encoding antigen 85A (Ag85A), Ag85B, or PstS-3 from ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium bovis Mycobacterium tuberculosis Peptides Abstract: We previously demonstrated that Bacillus Calmette-Guerin (BCG) immunization activated D(b) ...
Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.
Interferon-gamma Interleukin-2 mice Vaccination Vaccines, DNA Abstract: C57BL /6 mice were vaccinated with plasmid DNA encoding Ag85 from Mycobacterium tuberculosis, with Ag85 protein in adjuvant, or with a combined ...
CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.
Vaccination Vaccines, DNA Abstract: The contribution of CD8 + and CD4 + T cell-mediated effector functions against Mycobacterium tuberculosis infection elicited by i.m. vaccination with plasmid DNA encoding the ...