Zoekresultaten - 26 results

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

8 (2018) Abstract: Viral infection, initiated by the landing of a virion on a cellular surface, is largely defined by the preliminary interactions established between viral particles and their receptors at ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

to 5-fold decrease in virion production due to interference with the viral RNA metabolism. Using single-round virus infection experiments we demonstrated that early HIV-1 replication also depends on ...

Incorporation of the influenza A virus NA segment into virions does not require cognate non-coding sequences.

The aim of this study is to better understand the role of the non-conserved non-coding sequences in the incorporation of the viral segments into virions. The NA-segment NC sequences were systematically ...

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

Viral Vaccines Virion Abstract: Bluetongue virus (BTV) is endemic in many parts of the world, often causing severe hemorrhagic disease in livestock. To date, at least 27 different serotypes have been ...

Experimental evidence for proteins constituting virion components and particle morphogenesis of bacteriophage ZF40.

363, Issue 6 (2016) Keywords: Bacteriophages Capsid Proteins Gene Order Genome, Viral Open Reading Frames Proteome Viral Proteins Virion Abstract: Bacteriophage ZF40 is the only currently available, ...

Deletion of Murid Herpesvirus 4 ORF63 Affects the Trafficking of Incoming Capsids toward the Nucleus.

associated with a defect in virion egress from the infected cells. In contrast, it appeared that MuHV-4 ORF63-deficient mutants failed to address most of their capsids to the nucleus during entry into the host ...

Evaluation of convenient pretreatment protocols for RNA virus metagenomics in serum and tissue samples.

also that direct sequencing of cDNA is recommended above an extra random PCR amplification step, and a that the virion enrichment strategy (filtration and nuclease treatment) has a beneficial effect for ...

The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae.

and 25% proteins considered homologous between the two clades. By ESI- MS / MS analysis we determined that their virions are composed of at least 25 different proteins and electron microscopy revealed ...

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles.

demonstrate that inhibition of LEDGF /p75- IN interaction by specific mutants or LEDGIN s precludes incorporation of LEDGF /p75 in virions, underscoring the specificity of the uptake. LEDGF /p75 depletion did ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

type representative of the giant phage genus, which is characterized by unusually large virions and genomes. By unraveling the transcriptional map of the approximately 280-kb varphiKZ genome to ...

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