Zoekresultaten - 66 results

Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.

1 (2020) Abstract: BACKGROUND: Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis in Asia. JEV infection of mice and humans can lead to an uncontrolled inflammatory response in the ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

to 5-fold decrease in virion production due to interference with the viral RNA metabolism. Using single-round virus infection experiments we demonstrated that early HIV-1 replication also depends on ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

essential cellular functions and promiscuous targets for many viruses. The screening pipeline was applied to the influenza A virus (IAV) PB2 polymerase proteins of five strains representing different levels ...

Reduced virulence of a pseudorabies virus isolate from wild boar origin in domestic pigs correlates with hampered visceral spread and age-dependent reduced neuroinvasive capacity.

mortality associated with pseudorabies virus (PRV) infection are dependent on the age of the pig and the virulence of the strain. PRV strains circulating in wild boar are considered to be low virulent, but no ...

Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.

and Us9 during BHV-1 infection in the respiratory mucosa. First, we constructed and characterized BHV-1 Us3 null, Us9 null and revertant viruses. Then, we analysed the viral replication and plaque size ...

Age-Dependent Differences in Pseudorabies Virus Neuropathogenesis and Associated Cytokine Expression.

induced by pseudorabies virus (PRV) infection of its natural host is inversely related to the age of the pig. During this study, 2- and 15-week-old pigs were inoculated with PRV strain NIA3. This resulted ...

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

recognized. Vaccination against all serotypes is necessary to protect susceptible animals and to prevent onward spread of the virus by insect vectors. In our previous studies, we generated replication ...

Experimental bluetongue virus superinfection in calves previously immunized with bluetongue virus serotype 8.

Etienne; Saegerman, Claude Source: Vet Res, Volume 47, Issue 1, p.73 (2016) Keywords: Animals Bluetongue Bluetongue virus Cattle Cattle Diseases Female Male Superinfection Viral Vaccines Abstract: The effect ...

A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds.

Transbound Emerg Dis, Volume 63, Issue 2, p.e205-12 (2016) Keywords: Animals Antibodies, Viral Antiviral Agents Disease Models, Animal Europe Foot-and-Mouth Disease Foot-and-Mouth Disease Virus Guinea Pigs ...

Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.

Glycosylation Leukemia Virus, Bovine Protein Interaction Domains and Motifs Protein Subunits Viral Envelope Proteins Viral Fusion Proteins Virus Attachment Virus Internalization Virus Replication Abstract: ...

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