Zoekresultaten - 280 results
Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
Antoine Francotte; Paul Stickings Source: Biologicals, Volume 71 (2021) Keywords: Animal Testing Alternatives Animals Antibodies, Monoclonal Immunoassay Tetanus Tetanus Toxoid Vaccine Potency Abstract: ...
Towards Real-Time and Affordable Strain-Level Metagenomics-Based Foodborne Outbreak Investigations Using Oxford Nanopore Sequencing Technologies
Flongle flow cell, on an extract treated with eukaryotic host DNA removal. Moreover, an alternative approach based on in silico DNA walking allowed to obtain rapid confirmation of the presence of ...
4DEMON: Integrating 40 Years of Data on PCB and Metal Contamination in Marine Sediments of the Belgian Part of the North Sea
highly standardized trend modeling approaches like those proposed by regional sea conventions such as OSPAR, named after the Oslo and Paris conventions.Therefore, we applied alternative approaches, ...
Whole Genome Sequencing Provides an Added Value to the Investigation of Staphylococcal Food Poisoning Outbreaks
during SFP outbreak investigation. Although confirming the production of enterotoxins remains important for SFP investigation, we delivered a proof-of-concept that WGS is a valid alternative and/or ...
Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based assay.
(e.g. virus neutralization assays), or are expensive with suboptimal specificity (e.g. commercial ELISA s and RDT s). Bead-based assays offer a cost-effective alternative and allow for multiplexing to ...
Particle size analysis of pristine food-grade titanium dioxide and E 171 in confectionery products: Interlaboratory testing of a SP-ICP-MS screening method and confirmation with transmission electron microscopy.
titanium dioxide nanomaterial according to the current EU regulatory requirements. The overall positive outcome of the method performance evaluation and the current lack of alternative standardised ...
Production of Alternaria Toxins in Yellow Peach (Amygdalus persica) upon Artificial Inoculation with Alternaria alternate
chromatography-tandem mass spectrometry (UHPLC- MS / MS). The results showed that the growth of A. alternate and the AT s production were dramatically affected by the storage temperature. At 28 °C, the fungi grew rapidly ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
the development of alternative testing strategies such as computational (predictive) models based on in vitro testing. However, the variations in in vitro experimental conditions can influence the ...
Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
having been specifically developed as alternatives to in vivo potency tests. These methods require at least one well characterised monoclonal antibody (mAb) that is specific for the target antigen. In this ...
A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the DAWn-Plasma trial.
absence of an alternative diagnosis. Patients are randomized in a 2:1 ratio to either standard of care and convalescent plasma (active treatment group) or standard of care only. The active treatment group ...