Zoekresultaten - 11 results

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.

a mutation such as E119V- NA is known, highly sensitive PCR-based genotypic assays can be used to identify the prevalence of such mutant influenza viruses in clinical samples. In this study, based on an ...

Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza

Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde; Xavier Saelens; Isabelle Thomas; Nancy Roosens Source: Trends in Biotechnology, Volume 38, Issue 4 (2020) Keywords: antiviral resistance INFLUENZA Next-generation sequencing ...

Real-time prediction of influenza outbreaks in Belgium.

season. In this paper, we present an approach for predicting the weekly ILI incidence in real-time by resorting to a dynamically calibrated compartmental model, which furthermore takes into account the ...

Co-circulation of influenza A(H1N1)pdm09 and influenza A(H3N2) viruses, World Health Organization (WHO) European Region, October 2018 to February 2019.

viruses circulated widely and detection levels in primary care and hospital settings were similar to past seasons. Hospitalisation data may suggest an increased susceptibility to A(H1N1)pdm09 virus in older ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

comparative interactomics of multiple strains is an effective strategy to highlight correlations between host proteome hijacking and biological or pathogenic traits. Here, we developed an interactomic pipeline ...

Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015-2016.

Volume 5 (2017) Keywords: infectious disease sequencing Surveillance whole genome Abstract: Whole-genome sequencing (WGS) has become an essential tool for public health surveillance and molecular ...

Incorporation of the influenza A virus NA segment into virions does not require cognate non-coding sequences.

incorporation of the viral segments was tested by real-time RT- PCR. An initial virus growth deficiency correlated to a specific defect in NA segment incorporation. Upon serial passages, growth properties were ...

Temperature sensitivity on growth and/or replication of H1N1, H1N2 and H3N2 influenza A viruses isolated from pigs and birds in mammalian cells.

from a wide range of animal species, aquatic birds being the reservoir for their genetic diversity. Avian influenza viruses can be transmitted to humans, directly or indirectly through an intermediate ...

The impact of regular school closure on seasonal influenza epidemics: a data-driven spatial transmission model for Belgium.

Dis, Volume 18, Issue 1 (2018) Abstract: BACKGROUND: School closure is often considered as an option to mitigate influenza epidemics because of its potential to reduce transmission in children and then ...

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