Zoekresultaten - 38 results
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
these 36 compounds within 18 min (including wash and equilibration step). It was validated for sensitivity, selectivity and matrix effects. Within an analysis time of 32 min, the UHPLC- DAD method could ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market
selectivity and matrix effects. Within an analysis time of 32 min, the UHPLC- DAD method could quantify 32 compounds (4 showed insufficient UV absorbance) and resulted in sufficient selectivity, necessary since ...
Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills
increased significantly. An important contributor to this trend is the availability of a wide variety of flavours used in e-liquid refills. However, the role of these flavouring components in the potential ...
Chemometrical analysis of fingerprints for the detection of counterfeit and falsified medicines
Keywords: aims an analysi analysis AS at Chemometrics Control Counterfeit Counterfeit medicines data detection health Literature Medicine Multivariate ON Practice PRACTICES public public health Public-health ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
an analytical method based on hydrophilic interaction liquid chromatography (HILIC) to identify and quantify the most frequently encountered illegal peptides on the European market. For this objective, ...
A new approach to define acceptance limits for hematology in external quality assessment schemes.
their corresponding assigned value (U-scores) was modeled by means of an adaptation of Thompson’s “characteristic function”. Quantile regression was used to investigate the percentiles of the U-scores for ...
Chemometrics and chromatographic fingerprints to classify plant food supplements according to the content of regulated plants.
supplements are gaining popularity, resulting in a broader spectrum of available products and an increased consumption. Next to the problem of adulteration of these products with synthetic drugs the presence of ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
IR data, using SIMCA as modelling technique. During validation of the model, using an external test set, 21 of 25 were correctly classified and six of the nine targeted plants showed no ...
Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future.
with CNV were visually impaired (P = 0.016). Projections of AMD showed an almost doubling of affected persons despite a decreasing prevalence. By 2040, the number of individuals in Europe with early AMD ...
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
issues in drug development, as illustrated by high rates of late-stage attritions in clinical development and postmarketing commitments required by regulatory institutions. In an effort to shift the ...