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VALGENT: A protocol for clinical validation of human papillomavirus assays.

comparison and validation of HPV assays in general and HPV genotyping tests in particular according to clinically relevant outcomes and for clinical applications endorsed by scientific evidence. STUDY DESIGN: ...

Clinical and Analytical Performance of the Onclarity HPV Assay Using the VALGENT Framework.

and values for the six individual types ranged from 0.78 (95% CI, 0.68 to 0.87) for HPV-52 to 0.96 (95% CI, 0.93 to 0.99) for HPV-16. These data suggest that the Onclarity assay offers applications for ...

Evidence regarding human papillomavirus testing in secondary prevention of cervical cancer.

cancer prevention methods. A summary is given from recent meta-analyses and systematic reviews on 3 possible clinical applications of human papillomavirus (HPV) testing: triage of women with equivocal or ...

Enhanced analysis of real-time PCR data by using a variable efficiency model: FPK-PCR.

range of data. By reconstructing the entire chain of cycle efficiencies, rather than restricting the focus on a ‘window of application’, one extracts additional information and loses a level of ...

How to evaluate emerging technologies in cervical cancer screening?

questions. We observe that good guidelines on assessment of evidence for screening questions are currently lacking. Guidelines for diagnostic research (STARD), involving systematic application of the reference ...

Pooled analysis of the accuracy of five cervical cancer screening tests assessed in eleven studies in Africa and India.

feasible and affordable early detection and management methods is a public health priority. Five screening methods, naked eye visual inspection of the cervix uteri after application of diluted acetic acid ...

European guidelines for quality assurance in cervical cancer screening: recommendations for collecting samples for conventional and liquid-based cytology.

a few seconds to avoid drying artefacts. According to local guidelines, one of these three methods may be preferred. Sampling with a cotton tip applicator is inappropriate. Similar procedures should be ...

Chapter 9: Clinical applications of HPV testing: a summary of meta-analyses.

AND METHODS: A summary is given from recently published meta-analyses on three possible clinical applications of human papillomavirus (HPV)- DNA testing: triage of women with equivocal or low-grade ...

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