Zoekresultaten - 612 results

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Integrated approaches to testing and assessment (IATA) Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de l'impact sur la santé ...

Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements

channels for their purchase. Therefore, some of these products may be ‘suspicious’ and a risk for consumers health.   This study aims at developing a screening approach for detection of four regulated plants ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: Joint 3R Symposium, Brussels, Belgium (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment (IATA) pollutants Health Topics:  ...

RE-Place: a tool to promote the use of alternatives to animal testing

Merelbeke, Belgium (2023) Keywords: 3Rs animal testing Knowledge sharing NAMs new approach methodologies Service:  Risques chimiques et physiques pour la santé Chemische en fysische gezondheidsrisico's ...

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.

environmental risk assessment oncolytic virus shedding Abstract: Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the ...

Building trust in new approach methodologies via the RE-Place project

in the Life Sciences, World Congress on Alternatives and Animal Use in the Life Sciences, Niagara Falls, Canada (2023) Keywords: 3Rs alternative approaches animal testing Database Knowledge sharing ...

Investigating years of life lost in Belgium, 2004-2019: A comprehensive analysis using a probabilistic redistribution approach

Publication Type: Peer reviewed scientific article Authors: Brecht Devleesschauwer; Aline Scohy; Robby De Pauw; Vanessa Gorasso; Anne Kongs; Elias Neirynck; Peter Verduyckt; Grant M A Wyper; Laura Van den Borre Source: Arch Public Health, Volume 81, Issue ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

Animal sources of antimicrobial-resistant bacterial infections in humans: a systematic review

The studies differed in their methodologies, conceptual approaches (bottom-up, top-down, and complex), definitions of the AMR hazard and outcome, the number and type of sources they addressed, and the ...

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