Zoekresultaten - 61 results
A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells
Service: Évaluation des risques et de l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Full text language: English Category: C32 FOS Classification: 3.03 ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
assessment Full text language: English Category: C32 FOS Classification: 3.03 Health sciences ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Birgit Mertens Source: Joint 3R Symposium, Brussels, Belgium (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment (IATA) pollutants Health Topics: ...
Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment
testing and assessment (IATA) Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de l'impact sur la santé Risico- en ...
A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance
impact assessment Full text language: English Category: C32 FOS Classification: 3.03 Health sciences ...
Mixtures of genotoxicants: does the principle of additivity apply?
l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Full text language: English Category: C31 FOS Classification: 3.03 Health sciences ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
en milieu Service: Évaluation des risques et de l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Full text language: English Category: C31 FOS ...
Development of an AOP-based IATA for genotoxicity
Integrated approaches to testing and assessment (IATA) Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de l'impact sur la santé ...
EBoD-FL. Guidelines for mapping the environmental burden of disease in Flanders
according to a coherent framework. To tackle this objective, the disease burden attributable to environmental stressors is estimated using comparative risk assessment (CRA). As this method determines the ...