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Zoekresultaten - 8 results

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

Mathys Source: Euro Surveill, Volume 24, Issue 11 (2019) Abstract: IntroductionIn 2007, a new federal legislation in Belgium prohibited non-biosafety level 3 laboratories to process culture tubes suspected ...

A Framework for the Risk Assessment and Management of Gene Drive Technology in Contained Use

Publication Type: Peer reviewed scientific article Authors: B. van der Vlugt; David D. Brown; Kathleen Lehmann; Amaya Leunda; Nicolas Willemarck Source: Applied Biosafety, Volume 23, Issue 1, Number ...

Critical Aspects for Detection of Coxiella burnetii.

mammalian species. Requirements for intracellular multiplication together with the necessity for biosafety level 3 facilities restrict the cultivation of C. burnetii to specialized laboratories. Development ...

Construction of Nontoxigenic Mutants of Nonproteolytic Clostridium botulinum NCTC 11219 by Insertional Mutagenesis and Gene Replacement.

botulinum are cumbersome because of biosafety and biosecurity concerns. In the present work, we report the construction of two nontoxigenic derivatives of the type E gIICb strain NCTC 11219. In the first ...

Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.

a biosafety point of view. Health Topics:  Santé et environnement Gezondheid en milieu Service:  Biosécurité et biotechnologie Bioveiligheid en biotechnologie Biosafety and biotechnology Manuscript versions:  ...

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test.

biosafety. All six BoNTs were quantitatively nicked into active di-chain toxins linked by a disulfide bridge. The materials were thoroughly characterized with respect to purity, identity, protein ...

Novel GMO-Based Vaccines against Tuberculosis: State of the Art and Biosafety Considerations.

in clinical trials. Indeed, these vaccines administered to volunteers raise biosafety concerns with respect to human health and the environment that need to be assessed and managed. Health Topics:  ...

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