Zoekresultaten - 81 results
Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines.
evaluate the complete picture of evidence, we propose conducting network meta-analyses (NMA) of intervention trials, mostly on intermediate disease markers. To rank food groups according to their impact, ...
HIV testing within general practices in Europe: a mixed-methods systematic review.
Trials as Topic Abstract: BACKGROUND: Late diagnosis of HIV infection remains a key challenge in Europe. It is acknowledged that general practitioners (GP s) may contribute greatly to early case finding, ...
Eight years after an international workshop on myotonic dystrophy patient registries: case study of a global collaboration for a rare disease.
1 (2018) Keywords: Clinical trials Myotonic dystrophy REGISTRIES Trial readiness Abstract: BACKGROUND: Myotonic Dystrophy is the most common form of muscular dystrophy in adults, affecting an estimated 10 ...
Risk to human and animal health related to the presence of 4,15-diacetoxyscirpenol in food and feed
established based on data obtained in clinical trials of DAS as an anticancer agent (anguidine) after intravenous administration to cancer patients. The CONTAM Panel considered these data as informative for the ...
Pre-exposure intradermal rabies vaccination: a non-inferiority trial in healthy adults on shortening the vaccination schedule from 28 to 7 days.
result in wider acceptance. Methods: We conducted a non-inferiority trial in 500 healthy adults comparing the safety and immunogenicity of a two-visit (day 0 and day 7) intradermal (ID) primary vaccination ...
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
of circulating antibodies is important for protection, we assessed whether maternal immunization affects the avidity of infant vaccine-induced IgG antibodies, in the frame of a prospective clinical ...
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
models, quantitative systems pharmacology models, MCP-Mod, and model averaging) and three methods for study design optimization (Fisher information matrix (FIM)-based methods, clinical trial simulations, ...
HPV-based cervical cancer screening- facts, fiction, and misperceptions.
of published data from clinical trials and large observational studies. Overall, there is strong and uniform evidence for the efficacy of HPV-based screening, and little evidence for the usefulness of ...
Rapport annuel- registre belge des maladies neuromusculaires 2015
disease and to improve recruitment for clinical trials. The patients’ recruitment increases every year since the registry’s creation in 2008. In 2015, a total number of 4670 patients were registered. The ...
Jaarverslag Belgisch register van neuromusculaire aandoeningen (BNMDR) 2015
and to improve recruitment for clinical trials. The patients’ recruitment increases every year since the registry’s creation in 2008. In 2015, a total number of 4670 patients were registered. The ...