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Zoekresultaten - 4 results

Evaluation of the immunogenicity of pBudCE4.1 plasmids encoding mycolyl-transferase Ag85A and phosphate transport receptor PstS-3 from Mycobacterium tuberculosis.

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb), remains a major health problem. The only currently available vaccine, BCG, confers only variable protection and an improved vaccine is urgently ...

Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

individuals, especially those with human immunodeficiency virus (HIV) coinfection. The adaptive immune response mediated by CD4 + and CD8 + T cells is known to confer protection against TB. Hence, vaccines ...

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine.

tuberculosis, antigen 85 (Ag85), induced substantial humoral and cell-mediated immune responses and conferred significant protection against challenge with live M. tuberculosis and M. bovis bacille ...

Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.

Salmonella genomic island (SGI) 1 (variant SGI1-K) conferring resistance to ampicillin, streptomycin, gentamicin, sulfamethoxazole and tetracycline. Phylogeographical analysis indicates this clone emerged in ...

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