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Zoekresultaten - 10 results

Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium

among hospitalized COVID-19 patients offered by the contrasted prime-boost vaccination schemes. These results can inform vaccine policy, and contribute to knowledge used for the development of strategies ...

Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.

routine manufacturing of batches, do not contribute to the proper development and qualification of the candidate product. Some considerations regarding suitability of premises for challenge manufacturing ...

Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.

exposure studies need to be safe and results should be meaningful, e.g. contribute to a better cure. Both in the US and in Europe, the level of Good Manufacturing Practice required is related to the phase of ...

Commentary on the MID3 Good Practices Paper.

Model-Informed Drug Discovery and Development (MID3) group in promoting greater consistency in practice, application, and documentation of M&S and considers the paper is an important contribution towards ...

European Pharmacopoeia biological reference preparation for poliomyelitis vaccine (inactivated)

Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: J. Martin; A. Daas; C. Milne; Alexandre Dobly (contributing scientist) Source: EDQM, Volume Pharmeuropa ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

innate responses and contributing to the development of specific adaptive immune responses. Novel adjuvants have been developed based on agonists of PRR s. Areas covered: Lipid pathogen-associated ...

Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.

Publication Type: Peer reviewed scientific article Authors: Ates, Gamze; Steinmetz, Fabian P; Doktorova, Tatyana Yordanova; Madden, Judith C; Rogiers, Vera Source: Regul Toxicol Pharmacol, Volume 76, p.74-8 (2016) Keywords: Administration, Cutaneous Anima ...

Evolution of the implementation of a quality management system in the Belgian laboratories for anatomic pathology

in 2015.   Conclusions The collaboration with the laboratories has contributed to the awareness of the laboratories to work in a quality environment. Close monitoring, adjustment and support by the IPH and ...

Headspace-gas chromatographic fingerprints to discriminate and classify counterfeit medicines.

pharmaceuticals. Moreover, the fingerprint approach might also contribute in the evaluation of the health risks different types of counterfeit medicines pose. In this study a number of genuine and counterfeit ...

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