Zoekresultaten - 12 results

Microbial quality analysis of falsified medicines seized by controling agencies

possible risks, exemplified by potentially dangerous real-life data, in order to safeguard this aspect of public health. Health Topics:  Illegal medicines Médicaments illégaux Illegale geneesmiddelen ...

Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements

were developed using ultra-high performance liquid chromatography with diode array detection. The obtained multidimensional fingerprint data for a herbal reference standard (absorbance × wavelengths ...

COMBINATION OF CHEMOMETRICS AND MULTIDIMENSIONAL FINGERPRINTING FOR DETECTION OF REGULATED PLANTS IN PLANT FOOD SUPPLEMENTS

fingerprints by performing a correlation analysis on the DAD data. Chemometric analysis was carried out using two approaches: 1. binary models for each plant separately and 2. multiclass models. The data were ...

Multidimensional Chromatographic Fingerprinting Combined with Chemometrics for the Identification of Regulated Plants in Suspicious Plant Food Supplements.

the chromatogram, a multidimensional fingerprint (absorbance × wavelength × retention time) was considered. This was achieved by selecting several wavelengths through a correlation analysis. The data ...

Clustering of Tadalafil API Samples According to their Manufacturer in the Context of API Falsification Detection

latter to obtain characteristic data for the different manufacturers, allowing the network laboratories to conduct authenticity tests for future samples, as well as to detect substandard and ...

Multidimensional Fingerprint Development for the Detection of Tribulus terrestris in Plant Food Supplements

multidimensional data and extract maximum information with the intention to create binary models for faster screening of plant food supplements. Health Topics:  Médicaments illégaux Illegal medicines Illegale ...

OMCL testing and the API working group: Part of the solution?

to obtain a global image of the sample, to compare to the batches of the (presumed) manufacturer and/or to the data of fingerpint studies performed in the past in order to detect falsifications. In the ...

Use of near infrared spectroscopy and chemometrics for the classification of different Cannabis spp. samples found in Belgium

analysis (PCA) is applied as exploratory data analysis. Soft independent modelling of class analogy (SIMCA) was used to build a binary classification model according to the Belgian legislation. All ...

GEONs API fingerprint project: Selection of analytical techniques for clustering of sildenafil citrate API samples

14 different manufacturers were collected throughout the Network. Fingerprint data was collected through Mid-Infrared spectroscopy, Raman spectroscopy, liquid chromatography for related substances, gas ...

European fingerprint study on omeprazole drug substances using a multi analytical approach and chemometrics as a tool for the discrimination of manufacturing sources

Offerlé; M. Bertrand Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 208 (2022) Keywords: Chemometrics Data fusion fingerprint OMCL network Omeprazole API Substandard and falsified products ...

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