Zoekresultaten - 12 results

Validation of an animal-free analytical method for the detection of bacterial endotoxins in human vaccines

Publication Type: Scientific poster, presentation or proceeding Authors: Flore Laurent; Laure Cuignet; Julien Lamme; Hanae Kachach; Zahra Boukhouchi; Geneviève Waeterloos Source: NA, VUB- Symposium 3R (2023) Keywords: Endotoxin " vaccine &quo ...

The GEONs API-fingerprint program: Tackling falsifications of APIs

casualties happened when altered API s escaped detection in routine analytical testing. Any form of tampering the content or information about the content might affect the quality of the API, the finished ...

CBD oils on the Belgian market: A validated MRM GC-MS/MS method for routine quality control using QuEChERS sample clean up

CBD content not always corresponds to the label claim. There is a pressing need to develop new analytical methods specifically developed to the assay of such oily samples. Analytical issues are, ...

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants

Keersmaecker Source: Genes, Volume 12, Issue 4 (2021) Keywords: SARS-CoV-2; COVID-19; variants; detection; RT-qPCR; in silico specificity evaluation; bioinformatics tool; WGS data; mismatches; primers and probes ...

Chemical and toxciological characterization of e-liquid cigarettes

e-liquid refills. First, a comprehensive literature search was performed to obtain an overview about the chemical composition of the e-liquids and the analytical methods used for their detection. Although the ...

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

(consisting of a total of 30 primers and probe sets) used for SARS-CoV-2 detection and the impact of the virus’ genetic evolution on four of them. The exclusivity of these methods was also assessed using the ...

Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium

a subsequent quantification method using ultra-high performance liquid chromatography with diode array detection (UHPLC- DAD) was also successfully validated. Next, real-life illegal antimicrobial samples, ...

Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.

emergence of superbugs. Therefore, simple and accurate analytical methods are necessary, which are capable to detect and quantify a wide range of antimicrobials in suspected illegal products. In this work, ...

Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market

treatment failures, stronger antimicrobial resistance and even the promotion of the emergence of superbugs. Therefore, simple and accurate analytical methods are necessary, which are capable to detect and ...

Analysis of illegal peptide drugs via HILIC-DAD-MS.

(MS) and quantification via UV. Validation was performed via accuracy profiles based on the ISO 17025 guideline. The obtained validated HILIC-method allows for the detection and quantification of the ...

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