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Zoekresultaten - 5 results

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

Organization priority. We previously developed a software tool,, which provided offline species identification and drug resistance predictions for from whole genome sequencing (WGS) data. Performance was ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

to counter the effect of the drug. This might lead to new strategies for the development of new/complimentary drugs. On the other hand, this response gives an view on the working mechanism of the drug. ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

might lead to new strategies for the development of new/complimentary drugs. On the other hand, this response gives an view on the working mechanism of the drug. Moreover, comparing the response of ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

drug and RNA-targeting probes were designed. Next, the RNA-based DST was developed in 96 well format. In short, 200 µl of a positively flagged MGITTM (BD) culture is spiked with a drug, while a replicate ...

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