Zoekresultaten - 3 results

Welfare-Adjusted Life Years (WALY): A novel metric of animal welfare that combines the impacts of impaired welfare and abbreviated lifespan.

lifespan at the time of premature death. To demonstrate the concept, we estimated WALY s for 10 common canine diseases, namely mitral valve disease, dilated cardiomyopathy, chronic kidney disease, diabetes ...

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

injection enabled sustained stimulation and expansion of Tregs without inducing Teff activation and prevented diabetes in NOD mice. After several weeks of IL2 production, mice responded normally to a viral ...

Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.

Diabetes, Volume 60, Issue 8, p.2076-85 (2011) Keywords: Animals Blood Glucose Calcium Cell Proliferation Diabetes Mellitus, Experimental Female Glucose Insulin Insulin-Secreting Cells Islets of Langerhans ...

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