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Zoekresultaten - 52 results

Pyrogen testing of phage therapeutic products

these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced  in a bacterial host strain, hence pyrogen ...

The analysis of cannabinoids in e-cigarette liquids using LC-HRAM-MS and LC-UV.

In Belgium, CBD-containing e-liquids with a total THC content lower than 0.2% (w/w) are currently legal. In order to verify the compliance of the different CBD-containing e-cigarette liquids that are ...

Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium

SARS-CoV-2 Omicron infection among hospitalized patients in Belgium, and if this effect is homogenous across different Omicron sub-lineages. Methods Observational data from existing national surveillance ...

The analysis of cannabinoids in e-cigarette liquids using LC-HRAM-MS and LC-UV

with a total THC content lower than 0.2% (w/w) are currently legal. In order to verify the compliance of the different CBD-containing e-cigarette liquids that are available to the Belgian population, ...

The GEONs API-fingerprint program: Tackling falsifications of APIs

Official Medicines Control Laboratory (OMCL) Network (GEON) different initiatives were taken to augment the analysis and market surveillance of API s used by the different manufacturers. Despite the efforts, ...

Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.

classified differently by various jurisdictions. Indeed, considerations for challenge agent manufacturing vary between countries due to differences in regulatory oversight, the categorization of the challenge ...

Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines.

Kris De Clercq Source: Vaccines (Basel), Volume 9, Issue 5 (2021) Abstract: Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin ...

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

available, we used the bioinformatics tool SCREENED and a total of 4755 publicly available SARS-CoV-2 genomes, downloaded at two different time points, to evaluate the specificity of 12 RT-qPCR tests ...

Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium

spectrometry (UHPLC- MS2) screening method is presented, taking only 15 minutes, for the identification of 36 different antimicrobials and 1 beta-lactamase inhibitor. Furthermore, upon identification, ...

Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.

agents, 1 antifungal agent and 1 beta-lactamase inhibitor, covering eleven different antibacterial classes, were selected. The UHPLC- MS screening method with gradient elution is able to selectively detect ...

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