Zoekresultaten - 12 results

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.

environmental risk assessment oncolytic virus shedding Abstract: Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the ...

Belgian Mosquitoes Are Competent for Japanese Encephalitis Virus and Readily Feed on Pigs, Suggesting a High Vectorial Capacity.

Abstract:, a day-active mosquito known to feed aggressively on humans, was reported as a nuisance species near an abandoned pigsty in Belgium. Since Japanese encephalitis virus (JEV) is an emerging zoonotic ...

Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety

water, the DNA was extracted with two classical commercial kits or with a kit performing depletion of the host DNA. The extracted DNA also was amplified or not using Phi29 polymerase. We showed that all ...

A Multifaceted Approach for Evaluating Hepatitis E Virus Infectivity In Vitro: Cell Culture and Innovative Molecular Methods for Integrity Assessment

Publication Type: Peer reviewed scientific article Authors: Tatjana Locus; Lambrecht, Ellen; Sophie Lamoral; Willems, Sjarlotte; Steven Van Gucht; Vanwolleghem, Thomas; Michael Peeters Source: Veterinary Sciences, Volume 10, Issue 12 (2023) Health Topics: ...

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants

proper detection of the virus. In the present study, 11 primers and probe sets investigated during the first study were evaluated again with 84,305 new SARS-CoV-2 unique genomes collected between June 2020 ...

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

(consisting of a total of 30 primers and probe sets) used for SARS-CoV-2 detection and the impact of the virus’ genetic evolution on four of them. The exclusivity of these methods was also assessed using the ...

Risk Classification of Zoonotic Microorganisms: Development of a One Health Approach Tool Applied to HPAI A H5N1 Viruses

Publication Type: Peer reviewed scientific article Authors: Aline Baldo; Sarah Welby; Chuong Dai Do Thi; Amaya Leunda; Philippe Herman; Didier Breyer Source: Applied Biosafety (2018) Health Topics:  Health and environment Santé et environnement Gezondheid ...

Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.

(2016) Keywords: Animals Containment of Biohazards Genetic Vectors Humans Measles Measles Vaccine Measles virus Membrane Cofactor Protein mice Oncolytic Virotherapy Vaccination Vaccines, Attenuated Virus ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

Journal of Virology, Volume 88, Issue 18, Number 10510, p.10501- 10510 (2014) Keywords: 0 Absence Activity article Bacterial Proteins Bacteriophages Belgium Beta Biology Cell data Development DNA ...

Environmental risk assessment of clinical trials involving modified vaccinia virus Ankara (MVA)-based vectors.

Animals Clinical Trials as Topic Genetic Therapy Genetic Vectors Hazardous Substances Humans Risk Assessment Vaccination vaccinia virus Viral Vaccines Abstract: The modified vaccinia virus Ankara (MVA) ...

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