Zoekresultaten - 6 results

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

spectra that are compared to reference spectra in databases, is accurate, fast and cost-effective compared to traditional biochemical and molecular techniques. For the identification of Mycobacteria, this ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

to counter the effect of the drug. This might lead to new strategies for the development of new/complimentary drugs. On the other hand, this response gives an view on the working mechanism of the drug. ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

a powerful tool as well. Analyses on susceptible strains provide information on the response to the stress a drug is causing, showing which mechanisms are activated to counter the effect of the drug. This ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Background Multidrug resistance of Tuberculosis strains (MDR- TB) are one of the major WHO health concerns. One of the challenges that hampers the effective response to MDR- TB is the long turnaround time of ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

components that affect aerobic respiration. This demonstrates that, besides the inhibition of cell wall synthesis, respiratory poisoning plays a fundamental role in the bactericidal effect of delamanid. ...

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