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Zoekresultaten - 37 results

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

Do genomic passports leave us more vulnerable or less vulnerable? Perspectives from an online citizen engagement

as a fundamental concern, while this has not received sufficient attention so far in genomics. Participants expressed their vulnerability in two ways. First, the genomic passport would inform them ...

Telacebec Interferes with Virulence Lipid Biosynthesis Protein Expression and Sensitizes to Other Antibiotics

Publication Type: Peer reviewed scientific article Authors: Zhou, Zhiyu; Wattiez, Ruddy; Constant, Patricia; Marrakchi, Hedia; Karine Soetaert; Vanessa Mathys; Fontaine, Véronique; Zeng, Sheng Source: Microorganisms, Volume 11, Issue 10 (2023) Health Topi ...

From b to y ions, a decade of experience with peptide and protein analysis

recombinant expression technologies, and peptide synthesis have led to an increased development of protein and peptide therapeutics. Due to improved and simplified manufacturing techniques, disregard for patent ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells

were developed based on an extended reference dataset of 38 chemicals including existing as well as newly generated gene expression data. Both unsupervised and supervised machine learning algorithms were ...

Sex difference in innate inflammatory response and macrophage polarization in Streptococcus agalactiae-induced pneumonia and potential role of microRNA-223-3p.

suggest that differential expression of miR-233-3p may impact macrophage polarization, thereby contributing to fine-tune sex differences in inflammatory response. Health Topics:  Surveillance de la santé et ...

The HLS19-COM-P, a new instrument for measuring communicative health literacy in interaction with ohysicians: development and validation in nine European countries

physicians, expressing their needs and desires for treatment, and asking clarifying questions. There is a lack of instruments combining communication and HL proficiency. Hence, the aim was to establish an ...

Methodological considerations in injury burden of disease studies across Europe: a systematic literature review.

studies. We included injury BoD studies that quantified the BoD expressed in YLL, YLD, and disability-adjusted life years (DALY) in countries within the European Region between early-1990 and mid-2021. ...

Healthy Data, an online citizen consultation about health data reuse – intermediate report

Citizens expressed a broad range of preferences regarding the information they wish to receive, the methods used to communicate with them and the opportunities that are provided with for engagement. Views ...

Listeria monocytogenes isolates from Cornu aspersum snails: Whole genome-based characterization and host-pathogen interactions in a snail infection model.

expression led only to an increase of necrotic non-apoptotic cells. Overall, this study provides significant insights into the genetic diversity of L. monocytogenes from snails, the genomic features of them ...

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