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Zoekresultaten - 28 results
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
methodologies (NAM s) to identify molecular events underlying the genotoxic mode of action of chemicals. Previously, we developed the GENOMARK biomarker, consisting of 84 genes selected based on whole genomics ...
In Silico Methods for Chromosome Damage.
Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...
Ecotoxicity profile of heavily contaminated surface water of two rivers in Tunisia
chronic ecotoxicity was observed in all the studied organisms, however, no genotoxic activity was detected. The presence of metals and textile disperse dyes could be associated with the ecotoxicological ...
Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data
investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Genotoxicity studies on plant growth promoting smoke-water and smoke-derived compounds using Vicia faba and Persea americana S10 metabolic activation
Publication Type: Peer reviewed scientific article Authors: Partoens, M.; Kulkarni, M.G.; M.E. Light; J.C. Chukwujekwu; Luc Verschaeve; Van Staden, J. Source: South African Journal of Botany, Volume 115, Number 275 (2018) Health Topics: Health and enviro ...
Genotoxicity and Antigenotoxicity of selected South African indigenous plants
Publication Type: Peer reviewed scientific article Authors: Makhuvele, R.; R.G. Matshoga; R. Antonissen; Pieters, L.; Luc Verschaeve; Elgorashi, E.E. Source: South African Journal of Botany, Volume 114, Number 99 (2018) Health Topics: Health and environm ...
Slurry photocatalytic membrane reactor technology for removal of pharmaceutical compounds from wastewater: Towards cytostatic drug elimination
compounds and their metabolites, as well as their degraded by-products have genotoxic and mutagenic effects. A major challenge of cytostatic removal stands in the fact that most drugs are delivered to ...
In vitro toxicity and genotoxic activity of aqueous leaf and fruit extracts of Ruscus hypophyllum L.
Physiologiae Plantarum, Volume 39, Issue 9 (2017) Keywords: Antigenotoxicity Comet assay Phenolic content Vitotox test Genotoxicity Ruscus hypophyllum L. Health Topics: Health and environment Santé et ...
Detection and Toxicity Evaluation of Pyrrolizidine Alkaloids in Medicinal Plants Gynura bicolor and Gynura divaricata Collected from Different Chinese Locations
& Biodiversity, Volume 14, Issue 2 (2017) Keywords: Cytotoxic activities genotoxic activities Gynura bicolor Gynura divercata Pyrrolizidine alkaloids Health Topics: Health and environment Santé et ...