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Zoekresultaten - 9 results
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
(i) assessment of the uptake and potential crossing of the intestinal barrier by NC, (ii) assessment of local effects, including inflammation and genotoxicity, on the gastrointestinal epithelia, and ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
methodologies (NAM s) to identify molecular events underlying the genotoxic mode of action of chemicals. Previously, we developed the GENOMARK biomarker, consisting of 84 genes selected based on whole genomics ...
In Silico Methods for Chromosome Damage.
Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...
IDENTIFICATION, PHYSICOCHEMICAL CHARACTERISATION AND PRELIMINARY RISK ANALYSIS OF TITANIUM DIOXIDE PARTICLES IN FACE MASKS Intermediate report TiO2-Mask COVID-19 project September 2021
safe to be used as a food additive because a concern for genotoxicity cannot be ruled out, it is advisable to issue precautionary standards to limit the presence of TiO2 particles in face masks. Health ...
Ecotoxicity profile of heavily contaminated surface water of two rivers in Tunisia
chronic ecotoxicity was observed in all the studied organisms, however, no genotoxic activity was detected. The presence of metals and textile disperse dyes could be associated with the ecotoxicological ...
Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data
investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...
Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population
hazard-related information. Based on the margin of exposure (MOE) approach, there is no health concern related to MOSH exposure for the Belgian population. For MOAH, which may be potentially genotoxic and ...