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Zoekresultaten - 9 results

The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)

Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

methodologies (NAM s) to identify molecular events underlying the genotoxic mode of action of chemicals. Previously, we developed the GENOMARK biomarker, consisting of 84 genes selected based on whole genomics ...

In Silico Methods for Chromosome Damage.

Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...

Ecotoxicity profile of heavily contaminated surface water of two rivers in Tunisia

chronic ecotoxicity was observed in all the studied organisms, however, no genotoxic activity was detected. The presence of metals and textile disperse dyes could be associated with the ecotoxicological ...

Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data

investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

hazard-related information. Based on the margin of exposure (MOE) approach, there is no health concern related to MOSH exposure for the Belgian population. For MOAH, which may be potentially genotoxic and ...

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