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Zoekresultaten - 15 results

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

were developed in January 2020 for initial in silico specificity evaluation and to verify whether the targeted loci are highly conserved. Now that more whole genome data have become available, we used ...

In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract

Hermans, Nina; Foubert, Kenn Source: Food and Chemical Toxicology (2019) Keywords: antigenotoxicity Erythrina latissima In vivo antihepatotoxic activity Leguminosae Prenylated flavonoids Abstract: Stem bark ...

Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.

rising numbers of misidentified E. coli samples at the National Reference Centre (NRC). In this paper, we describe two novel tools to enhance Shigella surveillance. First, we developed a low-cost ...

Application of whole genome data for in silico evaluation of primers and probes routinely employed for the detection of viral species by RT-qPCR using dengue virus as a case study.

immense amount of available sequence data renders this however a labour-intensive and complex task. RESULTS: We present a bioinformatics approach that enables in silico evaluation of primers and probes ...

Performance of in silico models for mutagenicity prediction of food contact materials

Toxicological Sciences, Volume 163, Issue 2 (2018) Keywords: (Q)SAR food contact materials In silico mutagenicity VALIDATION Abstract: In silico methodologies, such as (quantitative) structure-activity ...

Reference Module in Food Science: A Safety Evaluation of Printed Paper and Board Contaminants: Photo-Initiators as a Case Study

9780081005965 Keywords: contaminants dry food exposure food contact materials hazard identification in silico tools Market survey paper and board printing ink Risk Assessment toxtree TTC Health Topics:  Food ...

(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.

as in silico (i.e. computational) techniques gain more and more importance. In the current study, a new prioritization strategy for identifying potentially mutagenic substances was developed based on ...

In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.

Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...

Investigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.

Chemicals Agency (ECHA), in silico prediction tools (ToxTree and Derek Nexus(TM)) and the in vitro Vitotox(®) test for detecting DNA damage. By applying the decision tree, substances could be classified into ...

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