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Zoekresultaten - 24 results
In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract
Hermans; Kenn Foubert Source: Food and Chemical Toxicology (2019) Keywords: antigenotoxicity Erythrina latissima In vivo antihepatotoxic activity Leguminosae Prenylated flavonoids Abstract: Stem bark of ...
Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.
observation spurred the development of an in silico workflow which extracts the Shigella serotype from Next-Generation Sequencing (NGS) data, taking into account gene functionality. Both tools will be ...
Application of whole genome data for in silico evaluation of primers and probes routinely employed for the detection of viral species by RT-qPCR using dengue virus as a case study.
immense amount of available sequence data renders this however a labour-intensive and complex task. RESULTS: We present a bioinformatics approach that enables in silico evaluation of primers and probes ...
Performance of in silico models for mutagenicity prediction of food contact materials
Toxicological Sciences, Volume 163, Issue 2 (2018) Keywords: (Q)SAR food contact materials In silico mutagenicity VALIDATION Abstract: In silico methodologies, such as (quantitative) structure-activity ...
Reference Module in Food Science: A Safety Evaluation of Printed Paper and Board Contaminants: Photo-Initiators as a Case Study
9780081005965 Keywords: contaminants dry food exposure food contact materials hazard identification in silico tools Market survey paper and board printing ink Risk Assessment toxtree TTC Abstract: Abstract ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
methods such as in silico (i.e. computational) techniques gain more and more importance. In the current study, a new prioritization strategy for identifying potentially mutagenic substances was developed ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...
Investigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.
Chemicals Agency (ECHA), in silico prediction tools (ToxTree and Derek Nexus(TM)) and the in vitro Vitotox(®) test for detecting DNA damage. By applying the decision tree, substances could be classified into ...
In silico epitope analysis of unique and membrane associated proteins from Mycobacterium avium subsp. paratuberculosis for immunogenicity and vaccine evaluation.
evaluated in IFN-γ release assay. In summary, eleven M. avium subsp. paratuberculosis proteins were identified by in silico analysis and need to be further evaluated for their immunodiagnostic and vaccine ...
Design of multiplex assays for molecular subtyping of pathogens with the Luminex xMAP technology
temperatures, hybridization structures and specificity for different types of oligonucleotides, and thereby simulating the multiplex assays in silico can facilitate the design of multiplex assays by reducing time ...