Zoekresultaten - 331 results

Development, Validation and Application of a Targeted LC-MS Method for Quantification of Microcystins and Nodularin: Towards a Better Characterization of Drinking Water

Keywords: liquid chromatography Mass Spectrometry matrix effect Method validation microcystin WATER Abstract: Water availability and quality are two crucial factors contributing to a healthy and ...

Development, validation and application of multi-class methods for the analysis of food additives by liquid chromatography coupled to tandem mass spectrometry

aimed to develop an accurate and high-throughput analytical method enabling the simultaneous determination of additives from different functional classes to facilitate controls and generate occurrence ...

Development of a data-intensive centralized system for surveillance and outbreak investigation of bacterial pathogens using whole-genome sequencing

routine public health surveillance of bacterial pathogens by developing and integrating data analysis methods that fulfill the requirements of a public health institute. Additionally, the developed methods ...

Occurrence of (suspected) genotoxic flavoring substances in Belgian alcohol-free beers.

develop analytical methods for a wide range of compounds in various types of food and drinks. In order to improve the monitoring of flavoring substances, a versatile and accurate analytical method using the ...

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

pathogenicity and immune escape. Targeted SARS-CoV-2 sequencing of diagnostic and wastewater samples has been explored as an epidemiological surveillance method for the competent authorities. Currently, only the ...

The purity of tattoo inks, screening substances of high concern

implementing compound-specific restrictions. Methodology: A screening method based on LC-QqQ- MS was developed and validated for screening 40 substances of high concern in tattoo inks. An additional ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

Publication Type: Peer reviewed scientific article Authors: Antoine Francotte; Raphael Esson; Eric Abachin; Melissa Vanhamme; Alexandre Dobly; Bruce Carpick; Sylvie Uhlrich; Jean-François Dierick; Celine Vanhee Source: Talanta, Volume 236 (2022) Health To ...

In Vivo Kinetics and Biotransformation of Aflatoxin B1 in Dairy Cows Based on the Establishment of a Reliable UHPLC-MS/MS MethodDataSheet1.docx

a clearance period that ended with a single dose trial of an AFB1-contaminated diet of 40 μg kg−1 b.w. An ultra-high performance liquid chromatography tandem mass spectrometry method was developed and ...

Brussels region finances VUB research into alternatives to animal experiments

“So it is fundamental that these kinds of method can be developed. And even if in certain cases animal experiments remain a necessary evil, we must keep in mind the objective of drastically reducing ...

Strategy to Develop and Evaluate a Multiplex RT-ddPCR in Response to SARS-CoV-2 Genomic Evolution.

assays during and after the development of the assays. Besides this first essential in silico evaluation, a minimal set of testing was proposed to generate experimental evidence on the method performance, ...

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