Zoekresultaten - 9 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

catalogue of mutations to serve as a global standard for interpreting molecular information for drug resistance prediction. Methods: A candidate gene approach was used to identify mutations as associated with ...

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.

procedure or to MALDI- TOF system status in each centre. In conclusion, MALDI- TOF showed to be a highly reproducible method and suitable for its implementation for NTM  identification. Health Topics:  ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

and Sudan. METHODS: On April 29 and May 30, 2016, the Swiss and German National Mycobacterial Reference Laboratories independently triggered an outbreak investigation after four patients were diagnosed with ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

long-term follow-up of XDR- TB cases treated with a regimen containing meropenem-clavulanate (M/Clav). DESIGN: Retrospective observational case series study at a single hospital. METHODS: All hospitalised ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

desorption ionization-time of flight mass spectrometry (MALDI- TOF MS) has been increasingly introduced as a valuable method for the identification of bacteria and yeast1. This technique, which generates mass ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

using the approach called RNA tag-Seq, multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, linezolid, moxifloxacin and bedaquilin), twice ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

the Brüker Database v3.0. For organisms of the Mycobacterium tuberculosis complex, identifications were 100% correct, while the concordance with standard methods was a bit lower for Nontuberculous ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

phenotypic Drug Susceptibility Testing (DST). To counter this, new fast and sensitive DNA-based methods were successfully introduced over the last years. However, these (a) are based on the knowledge on ...

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