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Zoekresultaten - 36 results
In silico methods for chromosome damage
detail as a case study. Overall, it can be concluded that, although they are in general less developed than those for mutagenicity, in silic o tools for chromosome damage can provide valuable information, ...
Identification of flavouring substances of genotoxic concern present in e-cigarette refills
Vera; Eric Deconinck; Vanhaecke, Tamara Source: Food and Chemical Toxicology, Volume 147, Issue 111864 (2021) Keywords: (Q)SAR methodologies e-cigarettes genotoxicity mutagenicity Abstract: E-cigarettes ...
Comments on the “Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure” by Smith‐Roe et al.
female rats and mice following subchronic exposure. Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL.Environ Mol Mutagen ...
In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin
countries. The present study aims to evaluate the oral and inhalation toxicity as well as the mutagenic effects of the essential oil of Cymbopogon giganteus leaves (EOCG) from a sample collected in Benin. ...
Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays
reported to have carcinogenic and/or mutagenic properties, another possible negative health impact is their endocrine disrupting potential. Therefore, the aim of this study was to determine both the ...
In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment
effects of long-term exposure to ELF-(E) MF s on the genetic material and the impact of long-term pre-exposure to ELF-(E) MF s on the sensitivity of cells to the damage induced by known mutagens are needed. ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Sigrid; Rogiers, Vera; Doktorova, Tatyana Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Performance of in silico models for mutagenicity prediction of food contact materials
Toxicological Sciences, Volume 163, Issue 2 (2018) Keywords: (Q)SAR food contact materials In silico mutagenicity VALIDATION Abstract: In silico methodologies, such as (quantitative) structure-activity ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
Toxicol, Volume 106, Issue Pt A, Number 505, p.496-505 (2017) Keywords: Consumer Product Safety Food Contamination Food Packaging Humans Mutagenicity Tests Mutagens Abstract: Up till now, no harmonized EU ...
Antimutagenicity, antioxidant activity and cytotoxicity of n-tetracosanol, eiocosanoic acid and arjunolic acid isolated from Combretum microphyllum (Combretaceae)
acid exposure Follow Hepatocytes Human investigation LED medicinal plant methanol extract method methods Mutagens Mutation n-Tetracosanol ON plant Plant Extracts Plants PROCESSES result results ...