Zoekresultaten - 168 results

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance

Publication Type: Peer reviewed scientific article Authors: Van Poelvoorde, Laura; Vanneste, Kevin; De Keersmaecker, Sigrid; Thomas, Isabelle; Van Goethem, Nina; Van Gucht, Steven; Saelens, Xavier; Roosens, Nancy Source: Frontiers in Microbiology, Volume ...

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance.

circulating influenza viruses is mainly focused on the hemagglutinin gene. Whole-genome sequencing (WGS) enables tracking mutations across all influenza segments allowing a better understanding of the ...

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

Rodwell,; Mathys, Vanessa Source: Lancet Microbe, Volume 3, Issue 4 (2022) Keywords: Drug Resistance mutations Tuberculosis Abstract: Background: Molecular diagnostics are considered the most promising route ...

In silico methods for chromosome damage

pharmaceuticals. To this extent, a compound’s potential to induce gene mutations as well as chromosome damage needs to be addressed. For chromosome damage, i.e. the induction of structural or numerical chromosome ...

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

detection and quantification of mutations present at low abundances using the mutations defining the SARS-CoV-2 lineage B.1.1.7 (alpha variant) as a case study. Real sequencing data were in silico modified by ...

Strategy to Develop and Evaluate a Multiplex RT-ddPCR in Response to SARS-CoV-2 Genomic Evolution.

and reliable diagnostic testing to prevent and control the viral transmission. However, inaccurate results may occur due to false negatives (FN) caused by polymorphisms or point mutations related to the ...

Large diversity of linezolid-resistant isolates discovered in food-producing animals through linezolid selective monitoring in Belgium in 2019.

period. The presence of LR chromosomal mutations, transferable LR genes and their genetic organizations and other resistance genes, as well as LR isolate relatedness (from this study and the NCBI database) ...

Frequency of Participation in External Quality Assessment Programs Focused on Rare Diseases: Belgian Guidelines for Human Genetics Centers.

technological platforms, if possible through EQA s covering the technique, genotyping, and clinical interpretation; (2) the triennial assessment of the genotyping and interpretation of specific germline mutations ...

A molecular assay for rapidly distinguishing the AviPro SALMONELLA VAC T vaccine strain from wild-type field isolates

resistance testing, but this sometime leads to ambiguous results with major economic implications. In this study, we used whole-genome sequencing to identify conserved and specific mutations in resistance and virulence ...

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