Zoekresultaten - 3 results

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

genus Aphthovirus (family Picornaviridae) that is only to be manipulated in high-containment facilities, thus complicating research on and discovery of antiviral strategies against the virus. Bovine ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Cysteine Endopeptidases Drug Evaluation, Preclinical Genes, Reporter Humans Luciferases, Firefly Picornaviridae Protease Inhibitors Viral Proteins Abstract: Proteolytical cleavage of the picornaviral ...

2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus.

(FMDV). FMDV belongs to the Picornaviridae and has the potential to cause devastating epidemics in livestock. The 50% and 90% effective concentrations (EC50 and EC90) for inhibition of the FMDV-induced ...

QR code

QR code for this page URL