Zoekresultaten - 512 results

Falsification of biotechnology drugs: current dangers and/or future disasters?

falsified medical products in the developed world. In recent years, also biotechnology drugs (synthetic peptide drugs and protein drugs) have been reported to be prone for falsifications. Next to the ...

Estimating the Reliability of Low-Abundant Signals and Limited Replicate Measurements through MS2 Peak Area in SWATH

Keywords: MS2 peak area Abstract: Sequential windows acquisition of all theoretical fragment ions mass spectrometry (SWATH- MS) provides large-scale protein quantification with high accuracy and selectivity. ...

Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.

Koopmans; Rob van Binnendijk; Elien Vandermarliere Source: Sci Rep, Volume 8, Issue 1 (2018) Keywords: Mumps; vaccine Abstract: The surface proteins of the mumps virus, the fusion protein (F) and ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

incomplete understanding of the pathogenesis. MALT1 mediates activation of several immune cell types and is involved in the proliferation and survival of cancer cells. MALT1 acts as a scaffold protein for ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

König; Gijsbers, Rik; De Rijck, Jan; Debyser, Zeger Source: PLoS One, Volume 13, Issue 7 (2018) Abstract: The human immunodeficiency virus (HIV) depends on cellular proteins, so-called cofactors, to ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

acts as a scaffold protein for NF-κB signalling and a cysteine protease that cleaves substrates, further promoting the expression of immunoregulatory genes. Deregulated MALT1 activity has been associated ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

polymerase Abstract: The optimized exploitation of cell resources is one cornerstone of a successful infection. Differential mapping of host-pathogen protein-protein interactions (PPI s) on the basis of ...

Microwave effects on DNA and Proteins

Publication Type: Scientific book or chapter Authors: Geddes, Chris D.; Luc Verschaeve Source: Misleading Scientific Papers on Health Effects from Wireless Communication Devices, Springer International Publishing, Issue 5, Number 23301/01/2017, Baltimore, ...

Quality and risk assessment of Illegal peptide drugs

Publication Type: Scientific poster, presentation or proceeding Authors: Steven Janvier Source: Tuesday Seminar, WIV-ISP, WIV-ISP (2017) Keywords: Illegal medicines Peptides Proteins Health Topics:  ...

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.

Combination Gene Dosage Genetic Markers Geography Haplotypes Humans Malaria, Falciparum Mutation Plasmodium falciparum Polymorphism, Genetic Protozoan Proteins Abstract: Malaria is a major public health problem ...

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