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Zoekresultaten - 2 results

In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials

luciferase gene, as a reporter gene, and a DNA responsive element specific to the human oestrogen receptor. The biological activity of a chemical compound is monitored by the measurement of light emitted by ...

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

discriminative power and sensitivity. Additionally, the peroxisome proliferator activated receptor γ (PPAR γ) dependency of the positive compounds was evaluated using PPAR γ activation and antagonist experiments. ...

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