Zoekresultaten - 8 results

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

set of 5845 Illumina sequences. To give estimates of error rates, we use a prospectively collected dataset of 4362. Using culture based DST as the reference, we estimate to be 100%, 95%, 82%, 99% ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

of containing mycobacteria.AimTo present mycobacterial surveillance/diagnosis data from the Belgian National Reference Centre for mycobacteria (NRC) from 2007 to 2016.MethodsThis retrospective ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

objective means for recording the actual time spent on running laboratory assays. DESIGN: Multicentre prospective study conducted in six European Union (EU) reference TB  laboratories. RESULTS: A total of ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

and Sudan. METHODS: On April 29 and May 30, 2016, the Swiss and German National Mycobacterial Reference Laboratories independently triggered an outbreak investigation after four patients were diagnosed with ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

isolates of genotype MST91 and comparison with two well-studied M. avium subsp. hominissuis reference strains i.e. Mah 104 and Mah TH135, identified in the two MST22 isolates nine specific virulence factors ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

spectra that are compared to reference spectra in databases, is accurate, fast and cost-effective compared to traditional biochemical and molecular techniques. For the identification of Mycobacteria, this ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

constructed and sequenced using the HiSeq technology (Illumina®). Reads were mapped to the reference genome and normalized read counts were calculated per gene.   Results: For each drug a specific ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

(Illumina®). Reads were mapped to the reference genome and normalized read counts were calculated per gene.   Results: For each drug a specific transcriptional response was mapped, revealing lists of up- and ...

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