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Zoekresultaten - 8 results

Pyrogen testing of phage therapeutic products

these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced  in a bacterial host strain, hence pyrogen ...

Characterization of a Bacteriophage GEC_vB_Bfr_UZM3 Active against.

drug-resistant human pathogens, but cases of the refractory infections, caused by strains that are not susceptible to the common antibiotic regimes established for have been more frequently reported. ...

Poor antibody response to BioNTech/Pfizer COVID-19 vaccination in SARS-CoV-2 naïve residents of nursing homes.

vaccination than naïve staff. These poor responses involved lower levels of IgG to all spike domains, lower avidity of RBD IgG, and lower levels of Ab neutralizing the vaccine strain. No naïve resident had ...

Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.

Publication Type: Peer reviewed scientific article Authors: Isabelle Bekeredjian-Ding; Jean-Hugues Trouvin; Hilde Depraetere; Carine La; Akamol E Suvarnapunya; Alan Bell; Alex Mann; Pauline Meij; Jeffrey M Bethony; Linda Schellhaas; Nazziwa, Winfred Badan ...

Characterization of Clostridium tetani seed strains – DNA seq/RNA seq/ targeted proteomics

Publication Type: Scientific poster, presentation or proceeding Authors: Jeroen Pennings; Celine Vanhee Source: VAC2VAC annual meeting (2021) Health Topics:  Effectiveness and safety of vaccines, medicines and health products- Quality of medical laborator ...

Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.

challenge agents; a focus on strain selection, in particular with regard to strain infectivity, stability and purity; the use of whole genome sequencing; a reference repository of challenge agents, the need ...

Quantification of Tetanus neurotoxin producted by Clostridium tetani strains

Publication Type: Scientific poster, presentation or proceeding Authors: Antoine Francotte; Celine Vanhee Source: VAC2VAC anual meeting (2019) Health Topics:  Effectiveness and safety of vaccines, medicines and health products- Quality of medical laborato ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

vaccine production. One of the major critical points in the manufacturing of these vaccines is the stable and reproducible production of high levels of toxin by the bacterial seed strains. In order to ...

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