Concomitant NA and NS deletion on avian Influenza H3N1 virus associated with hen mortality in France in 2019.
Santé animale
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Briand, François-Xavier [3]; Audrey Schmitz [4]; Axelle Scoizec [5]; Chantal Allée [6]; Rachel Busson [7]; Carole Guillemoto [8]; Hélène Quenault [9]; Lucas, Pierrick [10]; Isabelle Pierre [11]; Louboutin, Katell [12]; Cécile Guillou-Cloarec [13]; Claire Martenot [14]; Martine Cherbonnel-Pansart [15]; Rodolphe Thomas [16]; Pascale Massin [17]; Florent Souchaud [18]; Yannick Blanchard [19]; Mieke Steensels [20]; Bénédicte Lambrecht [21]; Nicolas Eterradossi [22]; Sophie Le Bouquin [23]; Eric Niqueux [24]; Béatrice Grasland [25]Mots-clés
Résumé:
An H3N1 avian influenza virus was detected in a laying hens farm in May 2019 which had experienced 25% mortality in Northern France. The complete sequencing of this virus showed that all segment sequences belonged to the Eurasian lineage and were phylogenetically very close to many of the Belgian H3N1 viruses detected in 2019. The French virus presented two genetic particularities with NA and NS deletions that could be related to virus adaptation from wild to domestic birds and could increase virulence, respectively. Molecular data of H3N1 viruses suggest that these two deletions occurred a…