Variability of iodine concentrations in the human placenta.
Public Access
Published
Auteurs
Kristof Y Neven [2]; Cédric B D Marien [3]; Bam G Janssen [4]; Harry A Roels [5]; Nadia Waegeneers [6]; Nawrot, Tim S [7]; Ann Ruttens [8]Trefwoorden
Samenvatting:
Iodine is an essential trace element, necessary for the production of thyroid hormones, which play a key role in optimal foetal growth and (neuro-) development. To date, iodine deficiency remains a health burden in many countries. We investigated the variability of placental iodine concentrations within and between individuals. We used 20 mother-neonate pairs from the ENVIRONAGE birth cohort, took samples at three standardized locations of the placentas, pooled and digested them, and determined the iodine concentrations using an ICP-MS method as an alternative for the Sandell-Kolthoff metho…