Dual DNA Barcoding for the Molecular Identification of the Agents of Invasive Fungal Infections.
Auteurs
Min Thuy Vi Hoang [3]; Irinyi, Laszlo [4]; Sharon C A Chen [5]; Sorrell, Tania C [6]; Meyer, Wieland [7]Trefwoorden
Article written during project(s) :
Samenvatting:
Invasive fungal infections, such as aspergillosis, candidiasis, and cryptococcosis, have significantly increased among immunocompromised people. To tackle these infections the first and most decisive step is the accurate identification of the causal pathogen. Routine identification of invasive fungal infections has progressed away from culture-dependent methods toward molecular techniques, including DNA barcoding, a highly efficient and widely used diagnostic technique. Fungal DNA barcoding previously relied on a single barcoding region, the internal transcribed spacer (ITS) region. However…