Search results - 44 results
Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies
the characterized iron (hydr)oxides and copper oxides. These cover both the in vitro genotoxicity tests that are currently recommended by EFSA which are adapted for nanomaterials and materials ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
chemical and biological techniques was used, to better reflect the risks to health and the environment. The samples investigated induced significant in vitro aryl hydrocarbon receptor (AhR) agonistic ...
Rational arguments for regulatory acceptance of consistency testing: benefits of non-animal testing over release testing of vaccines.
techniques to measure critical quality attributes. However, introduction of in vitro alternatives to replace in vivo release assays of authorized vaccines is challenging. AREAS COVERED: This report describes ...
Praktijkrichtlijn voor het opzetten van een kwaliteitssysteem in de erkende laboratoria voor pathologische anatomie werkzaam binnen het kader van het Erkenningsbesluit
2017/746 van 5 april 2017 betreffende de medische hulpmiddelen voor In-Vitro Diagnostiek (IVDR). Volgens de IVDR (van toepassing met ingang op 26 mei 2022) mogen in de laboratoria alleen nog CE gelabelde IVD ...
Flanders and Brussels join forces to tackle animal testing
methods from various research fields and research fields and institutions. This includes using human material in cell and tissue cultures (in vitro), or computer models (in silico). “These new, innovative ...
Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.
Volume 50, Issue 1 (2019) Keywords: Animals Chickens Gene Expression Regulation Genome, Viral Hemagglutination Inhibition Tests Immunity, Innate In Vitro Techniques Influenza A Virus, H9N2 Subtype ...
Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens.
objectives of this study were twofold: (i) to develop in vitro assays and molecular tools to detect the VP2 protein and gene and (ii) to evaluate cell-mediated immunity (CMI) induced by rHVT- IBD vaccination ...
Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines
control and eliminate TB, a better vaccine, efficient drug treatments and more rapid and cheaper diagnostic techniques are needed. In this PhD thesis we have attempted to provide additional information to ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
methods such as in silico (i.e. computational) techniques gain more and more importance. In the current study, a new prioritization strategy for identifying potentially mutagenic substances was developed ...
In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.
Source: Skin Pharmacol Physiol, Volume 29, Issue 6, p.300-308 (2016) Keywords: Adult Drug and Narcotic Control Female Humans Hydroquinones In Vitro Techniques Male middle aged Reproducibility of Results ...