Search results - 21 results
Identification of diffusion routes of O/EA-3 topotype of foot-and-mouth disease virus in Africa and Western Asia between 1974 and 2019- a phylogeographic analysis.
evolutionary phylodynamics of the causative serotype O viral strains all belonging to the East-Africa 3 topotype (O/ EA-3). We analyzed a total of 489 sequences encoding the FMDV VP1 genome region generated from ...
Complex Circulation of Foot-and-Mouth Disease Virus in Cattle in Nigeria.
Clercq Source: Front Vet Sci, Volume 7 (2020) Keywords: foot-and-mouth disease (FMD) Foot-and-Mouth Disease Virus Nigeria Phylogeny topotypes. VP1 Abstract: Nigeria is a large densely populated country in ...
Relation between broiler and human Campylobacter jejuni strains isolated in Belgium from 2011 to 2013.
typing, antibiotic microbiological resistance profiling (AMR p), lipooligosaccharide class typing or virulence gene profiling (Vp). Clusters containing both human and broiler meat strains were more common ...
Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens.
and more effective vaccination approaches, including the use of the recombinant turkey herpesvirus vaccine expressing the immunogenic structural VP2 protein of IBDV (recombinant HVT (rHVT)- IBD). The ...
Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria.
FMDV SAT1 in West Africa. The VP1 coding sequence of the Nigerian 2015 SAT1 isolates diverges from reported SAT1 topotypes resulting in a separate topotype. The reporting of a novel FMDV SAT1 strain in ...
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
binding domain and the VP16 activation domain. Firefly luciferase expression is dependent on cleavage of the transcription factor by the viral protease. This biosafe assay enables testing the effect of ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
binding site as BPIP or VP32947 at the top of the finger domain of the polymerase that is a “hot spot” for inhibition of pestivirus replication. Health Topics: Animal health Category: A1 FOS ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
virus was selected by serial passage of the virus in increasing drug-concentration. The BPIP-resistant virus (EC (50): 24+/-4.0 microM) proved cross-resistant with VP ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine [BPIP]and VP32947) is also resistant to AG110. AG110 did not inhibit the in vitro activity of recombinant BVDV RdRp but inhibited the activity of BVDV replication complexes (RC s). ...
Chicken recombinant antibodies specific for very virulent infectious bursal disease virus.
tool for the differentiation of vvIBDV strains. Immunoprecipitation studies revealed that CRA b 88 was directed towards a highly conformational epitope located within the major neutralizing protein VP ...